Does a high Mandard score really define a poor response to chemotherapy in oesophageal adenocarcinoma?

William R C KnightCara R BakerNyree GriffinWahyu WulaningsihMark KellyAndrew R DaviesJames A Gossagenull null

Published in: British journal of cancer (2021)

Patients with a complete nodal response to chemotherapy have significantly improved outcomes despite a poor Mandard score. High Mandard score does not correspond with a non-response to chemotherapy in all cases and patients with nodal downstaging may still benefit from adjuvant chemotherapy.

Keyphrases

locally advanced
neoadjuvant chemotherapy
lymph node
squamous cell carcinoma
rectal cancer
radiation therapy
chemotherapy induced
metabolic syndrome
skeletal muscle
insulin resistance
weight loss