Landmark Series: Neoadjuvant Treatment in Borderline Resectable Pancreatic Cancer.
Jin HeRichard D SchulickMarco Del ChiaroPublished in: Annals of surgical oncology (2021)
The definition of BRPC goes beyond the anatomic relationship between the tumor and vessels. We need to include biological and conditional dimensions. Neoadjuvant chemotherapy and surgery are associated with improved outcomes of BRPC. Understanding the molecular features of pancreatic cancer should lead to the discovery of novel biomarkers as well as a more personalized approach to guide individualized therapy.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- rectal cancer
- lymph node
- squamous cell carcinoma
- radiation therapy
- sentinel lymph node
- minimally invasive
- small molecule
- coronary artery bypass
- type diabetes
- bone marrow
- stem cells
- atrial fibrillation
- liver metastases
- percutaneous coronary intervention
- coronary artery disease
- skeletal muscle
- surgical site infection
- replacement therapy
- single cell
- smoking cessation