Evaluation of hydroxyurea genotoxicity in patients with sickle cell disease.

Emanuel Almeida Moreira de Oliveira Kenia de Assis Boy Ana Paula Pinho Santos Carla da Silva Machado Cibele Velloso-Rodrigues Pâmela Souza Almeida Silva Gerheim Leonardo Meneghin Mendonça

Published in: Einstein (Sao Paulo, Brazil) (2019)

In the study population, patients with sickle cell disease treated with the standard dose of hydroxyurea treatment did not show evidence of DNA damage induction.

Keyphrases

end stage renal disease
dna damage
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
oxidative stress
patient reported outcomes
sickle cell disease