Clinical and genomic predictors of adverse events in newly diagnosed glioblastoma.

Mary Jane Lim-Fat J Bryan Iorgulescu Rifaquat Rahman Varun M Bhave Alona Muzikansky Eleanor Woodward Sydney Whorral Marie Allen Mehdi Touat Xiaomei Li Gongwen Xu Jay Patel Elizabeth R Gerstner Jayashree Kalpathy-Cramer Gilbert Youssef Ugonma N Chukwueke J Ricardo McFaline-Figueroa Lakshmi Nayak Eudocia Quant Lee David A Reardon Rameen Beroukhim Raymond Y Huang Wenya Linda Bi Keith L Ligon Patrick Yung Wen

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

Genomic biomarkers based on functional variant analysis of a routine clinical panel may help identify adverse events in GBM, particularly seizures. Identifying these risk factors could improve the management of patients through better supportive care and consideration of prophylactic therapies.

Keyphrases

risk factors
newly diagnosed
healthcare
palliative care
copy number
quality improvement
pain management
affordable care act