HLA-B15:11 status and carbamazepine-induced severe cutaneous adverse drug reactions in HLA-B15:02 negative Chinese.

Christina Sze-Man Wong Desmond Yat-Hin Yap Patrick Ip Wilfred Hing-Sang Wong Gilbert T Chua Chi-Keung Yeung Henry Hin Lee Chan Janette S Y Kwok

Published in: International journal of dermatology (2021)

HLA-B*15:11 is a potential risk factor of CBZ-induced SCARs in HLA-B*15:02 negative Chinese patients. Further screening of HLA-B*15:11 status in those HLA-B*15:02 negative patients is recommended to avoid undesirable SCARs.

Keyphrases

adverse drug
high glucose
drug induced
diabetic rats
end stage renal disease
ejection fraction
risk factors
newly diagnosed
prognostic factors
emergency department
endothelial cells
oxidative stress
risk assessment
climate change
patient reported
human health
stress induced