CHD7 gene polymorphisms in female patients with idiopathic scoliosis.
Karolina BorysiakPiotr JanuszMirosław AndrusiewiczMałgorzata TokłowiczMateusz KozinogaTomasz KotwickiMałgorzata KotwickaPublished in: BMC musculoskeletal disorders (2020)
The polymorphism rs1017861 in CHD7 gene showed an association with IS susceptibility. Two polymorphisms (rs1017861 and rs4738813) were associated with curve severity and progression rate. None of the evaluated polymorphisms in CHD7 gene showed any association with the age of IS onset. Further evaluation of CHD7 gene should be considered as IS modifying factor.