Overrepresentation of pregnancies conceived by artificial reproductive technology in prenatally identified fetuses with Beckwith-Wiedemann syndrome.

John P JohnsonLinda BeischelCorbin SchwankeKatie StyrenAmy CrunkJonathan SchoofAbdallah F Elias

Published in: Journal of assisted reproduction and genetics (2018)

We found about a 20-fold overrepresentation of IVF cases in fetuses with BWS/omphalocele when compared with the rate of ART pregnancies in the USA (p < .0001). Our series provides support for an association of IVF and BWS. Patients should be counseled about these risks and made aware of the availability of prenatal diagnosis for detection.

Keyphrases

gestational age
pregnancy outcomes
preterm birth
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
hiv infected
pregnant women
patient reported outcomes
risk assessment
antiretroviral therapy
label free
climate change
quantum dots
real time pcr