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Acute pancreatitis secondary to oral contraceptive-induced hypertriglyceridemia: a case report.

Matheo Augusto Morandi StumpfAna Claudia Garabeli Cavalli KluthcovskyJefferson Matsuiti OkamotoGianna Carla Alberti SchrutPatricia de Oliveira CajoeiroAna Paula Marte ChacraRicardo Bizeli
Published in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2018)
Hypertriglyceridemia is the third most common cause of acute pancreatitis. Among the causes that lead to secondary hypertriglyceridemia, the use of contraceptive agents is the main reason to be assessed in young women. We report a case of a 31-year-old woman who had suffered two acute pancreatitis episodes secondary to hypertriglyceridemia. In the investigation, the previous medical team indicated a genetic screening before ruling out all secondary causes. LPL, apo CII and apo AV genes were negative for mutations. In the first appointment with us, the patient reported the use of a contraceptive agent for about 2 years. She was instructed to discontinue the drug. After one year of follow-up, her serum triglycerides are within the normal range and a copper intrauterine device was the method chosen by the patient for contraception.
Keyphrases
  • patient reported
  • healthcare
  • case report
  • drug induced
  • emergency department
  • gene expression
  • high glucose
  • endothelial cells
  • transcription factor
  • adverse drug