Urinary Exosomes Identify Inflammatory Pathways in Vancomycin Associated Acute Kidney Injury.

Linda AwdishuAmy LeJordan AmatoVidhyut JaniSoma BalRobert H MillsMarvic Carrillo-TerrazasDavid J GonzalezAshita TolwaniAnjali AcharyaJorge CerdáMelanie S JoyPaola NicolettiEtienne MacedoSucheta VaingankarRavindra MehtaSatish P RamachandraRaonull On Behalf Of The Direct Investigators

Published in: International journal of molecular sciences (2021)

Urinary exosomes reveal up-regulation of inflammatory proteins after nephrotoxic injury in V-AKI. Further studies are necessary in a large patient sample to confirm these findings for elucidation of pathophysiologic mechanisms and validation of potential injury biomarkers.

Keyphrases

acute kidney injury
mesenchymal stem cells
cardiac surgery
stem cells
oxidative stress
genome wide
methicillin resistant staphylococcus aureus
single cell
bone marrow
risk assessment