Altered prefrontal signaling during inhibitory control in a salient drug context in cocaine use disorder.
Ahmet O CeceliMuhammad A ParvazSarah KingMatthew SchaferPias MalakerAkarsh SharmaNelly Alia-KleinRita Z GoldsteinPublished in: Cerebral cortex (New York, N.Y. : 1991) (2022)
Results suggest altered involvement of cognitive control regions (e.g. dlPFC) during inhibitory control under a drug context, relative to an alternative reinforcer, in CUD. Supporting the iRISA model, these results elucidate the direct impact of drug-related cue reactivity on the neural signature of inhibitory control in drug addiction.