Evaluation and Comparison of Real-World Databases for Conducting Research in Patients With Colorectal Cancer.

Ching-Yu Wang Changxia ShaoAlicia C McDonaldMayur M AmonkarWei ZhouEdward A Bortnichak Xinyue Liu

Published in: JCO clinical cancer informatics (2023)

Compared with other databases, GENIE-BPC had the youngest patients with CRC with the most advanced disease and the largest proportion of patients receiving treatment. Investigators should consider adjustments when extrapolating results from clinico-genomic databases to the general CRC population.

Keyphrases

big data
copy number
machine learning
combination therapy
gene expression
artificial intelligence
dna methylation
deep learning
clinical evaluation
replacement therapy