Melatonergic signalling instructs transcriptional inhibition of IFNGR2 to lessen interleukin-1β-dependent inflammation.

Yaoyao XiaQingzhuo ZhangYuyi YeXiaoyan WuFang HeYuanyi PengYulong YinWenkai Ren

Published in: Clinical and translational medicine (2022)

Our conceptual framework provides potential therapeutic targets to prevent and/or treat inflammatory diseases associating with excessive IL-1β production.

Keyphrases

oxidative stress
gene expression
weight gain
transcription factor
heat shock
body mass index