Dosing of factor VIII concentrate by ideal body weight is more accurate in overweight and obese haemophilia A patients.

Iris van Moort Tim PreijersHendrika C A M HazendonkRoger E G SchutgensBritta A P Laros-van GorkomLaurens NieuwenhuizenFelix J M van der MeerKarin C J Fijnvandraat Frank W G Leebeek Karina MeijerRon A A MathôtMarjon H Cnossennull null

Published in: British journal of clinical pharmacology (2020)

IBW is the most suitable morphometric variable to explain interindividual FVIII PK variability and is more appropriate to dose overweight and obese patients.

Keyphrases

body weight
obese patients
bariatric surgery
end stage renal disease
newly diagnosed
chronic kidney disease
weight loss
prognostic factors
gastric bypass
peritoneal dialysis
physical activity
mass spectrometry