Novel CB1 receptor antagonist BAR-1 modifies pancreatic islet function and clinical parameters in prediabetic and diabetic mice.

Lesly Nava-MolinaToyokazu Uchida-FuentesHéctor Ramos-TovarMartha Fregoso-PadillaMarco Aurelio Rodríguez-MonroyAna Victoria Vega Gabriel Navarrete-VazquezErik Andrade-JorgeRafael Villalobos-MolinaRicardo Ortiz-OrtegaAlonso Vilches-Flores

Published in: Nutrition & diabetes (2020)

BAR-1 induces improvement of islet function, isolated from both prediabetic and diabetic mice. Effects of BAR-1 suggest a possible interaction with other cannabinoid receptors.

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