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Repeated SARS-CoV-2 vaccination in cancer patients treated with immune checkpoint inhibitors: induction of high-avidity anti-RBD neutralizing antibodies.

Caruso TeresitaSalani FrancescaCatanese SilviaFederico PratesiMercinelli ChiaraMotta GiuseppeGenovesi VirginiaBonato AdeleSara GalimbertiMasi GianlucaMigliorini Paola
Published in: International journal of clinical oncology (2023)
The data indicate that in cancer patients mRNA vaccine induces high avidity anti-RBD antibodies and neutralizing antibodies that increase after the third dose. The process of induction and selection of high-affinity antibodies is apparently unaffected by the treatment with anti-PD-1 or anti-PD-L1 antibodies.
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