Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor.

Benedikt FelsArne BeyerVioleta Cazaña-PérezTeresa GiraldezJuan Francisco Navarro-González Diego Alvarez de la Rosa Franz Schaefer Aysun Karabay BayazıtŁukasz ObryckiBruno RanchinJohannes Holle Uwe QuerfeldKristina Kusche-Vihrog

Published in: International journal of molecular sciences (2022)

These data indicate progressive structural damage of the endothelial surface with diminishing kidney function and identify the MR as a mediator of CKD-induced endothelial dysfunction.

Keyphrases

chronic kidney disease
end stage renal disease
endothelial cells
high glucose
multiple sclerosis
diabetic rats
oxidative stress
electronic health record
big data
magnetic resonance
drug induced
contrast enhanced
machine learning
data analysis