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Pattern of failure and clinical value of local therapy for oligo-recurrence in locally advanced non-small cell lung cancer after definitive chemoradiation: Impact of driver mutation status.

Jinmeng ZhangJiuang MaoDayu XuShanshan JiangTiantian GuoYue ZhouLi ChuXi YangXiao ChuJianjiao NiZhengfei Zhu
Published in: Cancer medicine (2022)
LA-NSCLC patients receiving definitive CRT generally had similar PFS and pattern of treatment failure, regardless of driver mutation status. Additional TKI therapy besides definitive CRT could prolong PFS but not OS. The majority of recurrent disease after definitive CRT belongs to oligo-recurrence and salvage local therapy may provide survival benefit.
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