Long-term consequences of urinary tract infection in childhood: an electronic population-based cohort study in Welsh primary and secondary care.
Kathryn HughesRebecca Cannings-JohnHywel M JonesFiona V Lugg-WidgerTin Man Mandy LauShantini ParanjothyNick A FrancisAlastair Hay LeylandChristopher C ButlerLianna AngelJudith Van der VoortKerenza HoodPublished in: The British journal of general practice : the journal of the Royal College of General Practitioners (2024)
The prevalence of renal scarring in an unselected population of children with UTI is low. Without underlying risk factors, UTI is not associated with CKD, hypertension, or ESRF by the age of 10 years. Further research with systematic scanning of children's kidneys, including those with less severe UTI and without UTI, is needed to increase the certainty of these results, as most children are not scanned. Longer follow-up is needed to establish if UTI, without additional risk factors, is associated with hypertension, CKD, or ESRF later in life.