Association of antibodies to Prevotella copri in anti-CCP-positive individuals at-risk for developing rheumatoid arthritis and in those with early or established rheumatoid arthritis.
Jennifer A SeifertElizabeth A BemisKristina RamsdenCassidy LowellKristen PolinskiMarie FeserChelsie L FleischerM Kristen DemoruelleJane BucknerPeter K GregersenRichard M KeatingTed R MikulsJames R O'DellMichael H WeismanKevin D DeaneJill M NorrisAllen C SteereV Michael HolersPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
These findings support a potential etiologic role for this microorganism in both RA preclinical evolution and the subsequent pathogenesis of synovitis.