Free water improves detection of changes in the substantia nigra in parkinsonism: A multisite study.

Edward OforiFlorian KrismerRoxana G BurciuOfer PasternakJohanna L McCrackenMechelle M LewisGuangwei DuNikolaus R McFarlandMichael S OkunWerner PoeweChristoph MuellerElke R GizewskiMichael SchockeChristian KremserHong LiXuemei HuangKlaus SeppiDavid E Vaillancourt

Published in: Movement disorders : official journal of the Movement Disorder Society (2017)

Free-water values in the posterior substantia nigra provide a consistent pattern of findings across patients with PD, MSA, and PSP in a large cohort across 3 sites. Free water in the posterior substantia nigra relates to clinical measures of motor and cognitive symptoms in a large cohort of parkinsonism. © 2017 International Parkinson and Movement Disorder Society.

Keyphrases

parkinson disease
drug induced
sleep quality
label free
quantum dots
deep brain stimulation