Uptake of KRAS Testing and Anti-EGFR Antibody Use for Colorectal Cancer in the VA.

Daniel J BeckerKyung M LeeSteve Y LeeKristine E LynchDanil V MakarovScott E ShermanChristy D Morrissey Michael J Kelley Julie A Lynch

Published in: JCO precision oncology (2021)

We found underuse of KRAS testing in advanced CRC, especially among older patients and those treated at lower-volume CRC centers. We found high rates of potentially guideline discordant underuse of EGFR mAb in patients with KRAS-WT tumors. Efforts to understand barriers to precision oncology are needed to maximize patient benefit.

Keyphrases

small cell lung cancer
wild type
epidermal growth factor receptor
tyrosine kinase
palliative care
case report
quality improvement