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Subjective Cognitive Complaint in Parkinson's Disease Patients With Normal Cognition: Canary in the Coal Mine?

Rachael PurriLaura BrennanJacqueline RickSharon X XieBenjamin L DeckLana M ChahineNabila DahodwalaAlice Chen-PlotkinJohn E DudaJames F MorleyRizwan S AkhtarJohn Q TrojanowskiAndrew SiderowfDaniel Weintraub
Published in: Movement disorders : official journal of the Movement Disorder Society (2020)
Patients with PD with normal cognition, but with SCC, report poorer cognition-specific functional abilities, and are more likely to be diagnosed with cognitive impairment and experience global functional ability decline long term. These findings suggest that SCC and worse cognition-related functional abilities may be sensitive indicators of initial cognitive decline in PD. © 2020 International Parkinson and Movement Disorder Society.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • white matter
  • cognitive impairment
  • risk assessment
  • depressive symptoms