Acute Myocarditis Following Vaccination With the First Dose of the mRNA-1273 Vaccine.
Abdulbaril OlagunjuAli MoradiBenjamin JohnsonZachary LebaronRoss JohnsonAzar MehdizadehPublished in: Journal of investigative medicine high impact case reports (2022)
Viral infections are a common cause of acute myocarditis. However, vaccines including influenza and smallpox have also been rarely implicated. Recently, the coronavirus disease 2019 (COVID-19) vaccines have been associated with acute myocarditis. We describe a case of acute myocarditis in a 19-year-old male 2 days after the initial dose of the COVID-19 mRNA-1273 vaccine. He presented with chest pain radiating to his left arm and bilateral shoulders. COVID, influenza, coxsackie, respiratory syncytial virus polymerase chain reaction (PCR) tests were negative. Electrocardiogram revealed diffuse ST-segment elevation. Initial Troponin was 15.7 ng/mL. A coronary angiogram revealed patent coronary arteries and no wall motion abnormality. A transthoracic echocardiogram showed diffuse hypokinesis with an ejection fraction of 49%. Cardiac magnetic resonance scan was aborted after 2 attempts due to severe claustrophobia. His chest pain resolved following initiation of aspirin, tylenol, colchicine, lisinopril, and metoprolol.
Keyphrases
- coronavirus disease
- liver failure
- sars cov
- respiratory failure
- ejection fraction
- magnetic resonance
- drug induced
- aortic dissection
- coronary artery disease
- coronary artery
- respiratory syncytial virus
- aortic stenosis
- respiratory syndrome coronavirus
- low dose
- computed tomography
- hepatitis b virus
- heart failure
- cardiovascular disease
- cardiovascular events
- binding protein
- high resolution
- mass spectrometry
- antiplatelet therapy
- atrial fibrillation