Plasma bradykinin and early diabetic nephropathy lesions in type 1 diabetes mellitus.
Kevin M WheelockJian CaiHelen C LookerMichael L MerchantRobert G NelsonGudeta D FufaaE Jennifer WeilHarold I FeldmanRamachandran S VasanPaul L KimmelBrad H RovinMichael MauerJon B Kleinnull nullPublished in: PloS one (2017)
Higher plasma bradykinin and related peptide concentrations measured before clinical onset of diabetic nephropathy in persons with T1D were associated with preservation of glomerular structures, suggesting that elevations of these kinin concentrations may reflect adaptive responses to early renal structural changes in diabetic nephropathy.
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