Serum VEGF-A and VEGFR-1 levels in patients with adult immunoglobulin A vasculitis.

Çiğdem Yücel Erdim Sertoglu Esra Firat OguzYıldız HayranAhmet OmmaTaner Özgürtaş

Published in: International journal of rheumatic diseases (2021)

This study is the first report indicating elevated serum VEGF-A, VEGFR-1, and more importantly VEGFR-1/VEGF-A ratio can be good representatives of the inflammatory processes together with vascular endothelial injury in adult IgAV patients. VEGFR-1 seems to be a more important indicator of the ongoing inflammation.

Keyphrases

vascular endothelial growth factor
endothelial cells
end stage renal disease
oxidative stress
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
patient reported outcomes
childhood cancer
young adults