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A case of biopsy-proven acute interstitial nephritis following atezolizumab-bevacizumab treatment of advanced unresectable hepatocellular carcinoma.

Reema PatelOmar ElghawyAmanda GibbsSrishti GuptaVarinder Kaur
Published in: Cancer reports (Hoboken, N.J.) (2024)
This case highlights the valuable role renal biopsy can play in accurately capturing irAEs and guiding appropriate management in the setting of ICI-induced AKI. It also exemplifies important considerations for steroid treatment of irAEs in the setting of comorbidities, such as diabetes.
Keyphrases
  • type diabetes
  • drug induced
  • ultrasound guided
  • high glucose
  • adipose tissue
  • intensive care unit
  • metabolic syndrome
  • skeletal muscle
  • endothelial cells
  • weight loss
  • metastatic colorectal cancer