Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms.

Katharina M DetjenRaik OttoYvonne GieseckeLukas GeislerPamela RiemerHenning JannCarsten GrötzingerChristine SersAndreas PascherTom LüddeUlf LeserBertram WiedenmannMichael SigalFrank TackeChristoph RoderburgLinda Hammerich

Published in: Cancers (2021)

We propose Flt3L as a prognostic biomarker for high grade GEP-NEN, harnessing its potential as a marker of an inflammatory tumor microenvironment. Flt3L measurements in serum, which can be easily be incorporated into clinical routine, should be further evaluated to guide patient stratification and treatment decisions.

Keyphrases

high grade
acute myeloid leukemia
tyrosine kinase
low grade
case report
oxidative stress
clinical practice
big data
deep learning