Immunomodulatory function of the cystic fibrosis modifier gene BPIFA1.

Aabida SaferaliAnthony C TangLisa J StrugBradley S QuonJames ZlosnikAndrew J SandfordSuzanne C Tough

Published in: PloS one (2020)

BPIFA1 and BPIFB1 have immunomodulatory activity and genetic variation associated with low levels of these proteins may increase CF lung disease severity.

Keyphrases

cystic fibrosis
pseudomonas aeruginosa
lung function
copy number
genome wide
transcription factor