Normative cut-offs for polycystic ovary syndrome (PCOS) diagnostic features in adolescents using cluster analysis.

In this novel study we define the normative diagnostic criteria cut-offs in this unselected adolescent population and show that these cut-offs correspond to lower percentiles than conventional cut-offs. These findings highlight the pertinent need to re-define PCOS diagnostic cut-offs in adolescents. Validation is required in larger, multi-ethnic and well characterised adolescent cohorts.