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Three-dimensional ultrastructural analysis and histomorphometry of collagen bundles in the periodontal ligament using focused ion beam/scanning electron microscope tomography.

Shingo HirashimaKeisuke OhtaTomonoshin KanazawaSatoko OkayamaAkinobu TogoYoshihiro MiyazonoJingo KusukawaKei-Ichiro Nakamura
Published in: Journal of periodontal research (2018)
These findings indicate that collagen bundles in horizontal fiber areas have high strength and that the tooth is firmly anchored to the alveolar bone by the horizontal fibers, but is not secured evenly to the alveolar bone. The tooth is firmly anchored around the cervical area, creating a "slingshot-like structure." This study has provided further insights into the structure of the PDL and forms the basis for the development of more effective therapies for periodontal tissue regeneration.
Keyphrases
  • electron microscopy
  • bone mineral density
  • wound healing
  • stem cells
  • soft tissue
  • bone loss
  • bone regeneration
  • tissue engineering
  • body composition
  • postmenopausal women
  • mass spectrometry
  • solar cells