Association of fibroblast growth factor 10 with the fibrotic and inflammatory pathogenesis of Graves' orbitopathy.

Sun Young JangSoo Hyun ChoiDon KikkawaEun Jig LeeJin Sook Yoon

Published in: PloS one (2021)

Our data demonstrate that FGF10 has beneficial effects on the inflammatory and fibrotic mechanisms of GO in primary cultured OFs, providing new insights into GO pathology and the discovery of FGF10 as a promising novel therapeutic application for the treatment of GO.

Keyphrases

systemic sclerosis
oxidative stress
idiopathic pulmonary fibrosis
small molecule
electronic health record
endothelial cells
high throughput
big data
combination therapy
machine learning
artificial intelligence