Frequency of microsatellite instability (MSI) in upper tract urothelial carcinoma: comparison of the Bethesda panel and the Idylla MSI assay in a consecutively collected, multi-institutional cohort.

Friederike KullmannPamela L StrisselReiner StrickRobert StoehrMarkus EcksteinSimone BertzBernd WullichDanijel SikicSven WachHelge TaubertPeter OlbertHendrik HeersMaría Fernanda LaraMaria Luisa MaciasElisa Matas-RicoMaria José LozanoDaniel PrietoIsabel HierroThomas van DoeverenIvan BiecheJulien Masliah-PlanchonRomane BeaurepereJoost L BoormansYves AlloryBernardo Herrera-ImbrodaArndt HartmannVeronika Bahlinger

Published in: Journal of clinical pathology (2021)

Our data indicate a low incidence rate of MSI tumours in patients with UTUC. Furthermore, our findings highlight that Idylla MSI Assay can be applied as an alternative method of MSI analysis for UTUC.

Keyphrases

high throughput
risk factors
deep learning
single cell
genetic diversity