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Single-atom-anchored microsweepers for H. pylori inhibition through dynamically navigated reciprocating locomotion.

Xinqi CaiZhiyang LiWen-Jing ZhouHui DengXiaoxu CaoJieqiong XuZhiwei YinShen WangXin XiaChao MaLong ChenDing DingWeihong TanZhuo Chen
Published in: Chemical communications (Cambridge, England) (2023)
Catalytic microsweepers with a single-iron-atom center were designed to search for and inhibit Helicobacter pylori . Under dynamic navigation, the microsweepers displayed a large-range wall-adhering reciprocating motion, which increased the opportunity for interaction between microsweepers and H. pylori and further inhibited H. pylori through acid-responsive reactive oxygen species generation.
Keyphrases
  • helicobacter pylori
  • reactive oxygen species
  • helicobacter pylori infection
  • molecular dynamics
  • electron transfer
  • cancer therapy
  • iron deficiency
  • mass spectrometry
  • high resolution