Overcoming the deceptively low viability of CD45+ cells in thawed cord blood unit segments.

Published in: Vox sanguinis (2019)

CB CD45+ cells are sensitive to red cell lysis treatment post-thaw; omission of this step provides the best viability and ultimately better reflects the quality of cells used for transplantation.

Keyphrases

induced apoptosis
cell cycle arrest
cord blood
cell death
cell therapy
cell proliferation
quality improvement
nk cells