Detection of Cell-Dissociated Non-Typeable Haemophilus influenzae in the Airways of Patients with Chronic Obstructive Pulmonary Disease.
Samantha J ThulbornAlessandro CeroniKoirobi HaldarVijay MistryJennifer L CaneChristopher E BrightlingMichael R BarerMona BafadhelPublished in: International journal of chronic obstructive pulmonary disease (2020)
In patients with COPD, NTHi can exist in both cell-associated and cell-dissociated forms. Cell-dissociated NTHi is associated with neutrophilic airway inflammation during exacerbations of COPD and may be a driving factor in worsening lung function during these episodes.