Identification of a Notch transcriptomic signature for breast cancer.
Eike-Benjamin BrauneFelix GeistXiaojia TangKrishna KalariJudy BougheyLiewei WangRoberto A Leon-FerreAntonino B D'AssoroJames N IngleMatthew P GoetzJulian KreisKang WangTheodoros FoukakisAnita SeshireDirk WienkeUrban LendahlPublished in: Breast cancer research : BCR (2024)
The 20-gene transcriptional signature will be a valuable tool to evaluate the response of future Notch-targeting therapies for breast cancer, to learn about potential effects on Notch signalling from conventional breast cancer therapies and to better stratify patients for therapy considerations.
Keyphrases
- end stage renal disease
- cell proliferation
- ejection fraction
- newly diagnosed
- gene expression
- peritoneal dialysis
- prognostic factors
- transcription factor
- genome wide
- stem cells
- single cell
- mesenchymal stem cells
- cancer therapy
- climate change
- copy number
- breast cancer risk
- patient reported outcomes
- rna seq
- patient reported