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Aerosolizable Plasmid DNA Dry Powders Engineered by Thin-film Freezing.
Haiyue Xu
Chaeho Moon
Sawittree Sahakijpijarn
Huy M Dao
Riyad F Alzhrani
Jie-Liang Wang
Robert O Williams
Zhengrong Cui
Published in:
Pharmaceutical research (2023)
It is feasible to use TFF to produce aerosolizable pDNA dry powder for pulmonary delivery, while preserving the integrity and activity of the pDNA.
Keyphrases
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escherichia coli
pulmonary hypertension
circulating tumor
cell free
single molecule
crispr cas
nucleic acid