Impact of major depression and antidepressant use on alcoholic and non-alcoholic fatty liver disease: A population-based study.

Abdel-Aziz ShaheenGilaad G KaplanKeith A SharkeyBrendan Cord LethebeMark G Swain

Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)

MDD was not associated with worse outcomes for ALD or NAFLD. Mirtazapine was associated with an increased risk of decompensated cirrhosis or death, which was not observed with other antidepressants. Prospective studies are warranted to confirm these findings.

Keyphrases

major depressive disorder
bipolar disorder
heart failure
liver injury
case control
ejection fraction
liver fibrosis
drug induced
metabolic syndrome
skeletal muscle