Determination of ertapenem in plasma and ascitic fluid by UHPLC-MS/MS in cirrhotic patients with spontaneous bacterial peritonitis.
Raul Rigo-BonninAlberto AmadorMaría Núñez-GárateVirgínia Mas-BoschAriadna PadullésSara Cobo-SacristánJosé CastellotePublished in: Advances in laboratory medicine (2023)
The measurement procedures based on UHPLC-MS/MS developed and validated in this study could be useful in pharmacokynetic and pharmacodynamic studies in subjects with liver cirrhosis who develop spontaneous bacterial peritonitis treated with ertapenem.