Cyclophosphamide-induced hemorrhagic cystitis in young patients with solid tumors: A single institution study.

Yoshimasa SaitoTadashi KumamotoMiki ShiraiwaTomoko SonodaAyumu ArakawaHironobu HashimotoIkumi TamaiChitose OgawaHiroyuki Terakado

Published in: Asia-Pacific journal of clinical oncology (2018)

Our supportive care measures may be effective in preventing CPA-induced HC. Patients who receive CPA doses < 1500 mg/m2 /day should get ≥125 mL/m2 /h of infused fluid, regardless of mesna usage; those who receive of CPA ≥1500 mg/m2 /day should also receive mesna and vigorous hydration.

Keyphrases

high glucose
diabetic rats
healthcare
physical activity
palliative care
drug induced
low dose
endothelial cells
high dose
oxidative stress