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CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension.

Xiaoyi HuYuanyuan SunShang WangHui ZhaoYaqin WeiJiaqi FuYuxia HuangWenhui WuJinling LiJinming LiuSu-Gang GongQinhua ZhaoLan WangRong JiangXiao SongPing Yuan
Published in: Journal of the American Heart Association (2024)
Our study sheds new light on circALMS1-regulated dysfunction of PMECs by the miR-17-3p/YTHDF2 pathway under hypoxia and provides insights into the underlying pathogenesis of PH.
Keyphrases
  • pulmonary hypertension
  • endothelial cells
  • oxidative stress
  • pulmonary artery
  • pulmonary arterial hypertension
  • transcription factor
  • mouse model