A novel histological index for evaluation of environmental enteric dysfunction identifies geographic-specific features of enteropathy among children with suboptimal growth.
Ta-Chiang LiuKelley VanBuskirkSyed A AliM Paul KellyLori R HoltzOmer H YilmazKamran SadiqNajeeha IqbalBeatrice AmadiSana SyedTahmeed AhmedSean MooreI Malick NdaoMichael H IsaacsJohn D PfeiferHannah AtlasPhillip I TarrDonna M DennoChristopher A MoskalukPublished in: PLoS neglected tropical diseases (2020)
We propose the first EED histology index for interpreting duodenal biopsies. This index should be useful in future clinical and translational studies of this widespread, poorly understood, and highly consequential disorder, which might be caused by multiple contributing processes, in different regions of the world.