Low dose IL-2 suppress osteoclastogenesis in collagen-induced arthritis via JNK dependent pathway.
Han SunYong ZhaoKun WangLi ZhuJian DongJie ZhaoYimin WangHuan LiXiaoliang SunJun-Zheng HuPublished in: Immunity, inflammation and disease (2020)
It is the first time for us to prove that low dose IL-2 can inhibit osteoclast formation in collagen-induced arthritis through the JNK dependent pathway, which will provide the angle and theoretical basis for future immunotherapy of IL-2.