S1P Signalling Axis Is Necessary for Adiponectin-Directed Regulation of Electrophysiological Properties and Oxidative Metabolism in C2C12 Myotubes.

Caterina BernacchioniRoberta SqueccoTania GamberiVeronica GhiniFabian SchumacherMichele MannelliRachele GarellaEglantina Idrizaj Francesca CencettiElisa PulitiPaola BruniPaola Turano Tania Fiaschi Chiara Donati

Published in: Cells (2022)

Altogether, these findings show that S1P biosynthesis is necessary for the electrophysiological properties and oxidative metabolism of Adn in skeletal muscle cells.

Keyphrases

skeletal muscle
induced apoptosis
insulin resistance
cell cycle arrest
metabolic syndrome
endoplasmic reticulum stress
oxidative stress
cell death
cell proliferation
pi k akt