A novel microRNA signature for the detection of melanoma by liquid biopsy.

Claudia SabatoTeresa Maria Rosaria NovielloAlessia CovreSandra CoralFrancesca Pia CarusoZein Mersini BesharatElena SplendianiLaura MasuelliCecilia BattistelliAlessandra VaccaGiuseppina CatanzaroAgnese PoAndrea AnichiniMichele MaioMichele CeccarelliAnna Maria Di GiacomoElisabetta Ferretti

Published in: Journal of translational medicine (2022)

We demonstrate that a blood test based on circulating microRNAs can non-invasively detect melanoma, offering a novel diagnostic tool for improving standard care. Moreover, we revealed an immune suppressive role for melanoma pEV-microRNAs.

Keyphrases

skin cancer
healthcare
palliative care
basal cell carcinoma
quality improvement
ionic liquid
pain management
label free
loop mediated isothermal amplification