A newly developed UPLC-MS/MS method for simultaneous quantitative analysis of ajuforrestin A, ajuforrestin B, ajugamacrin and 8-O-acetylharpagide derived from Ajuga plants in mice blood and the in vivo pharmacokinetics.
Xiuwei ShenChen ChenCongcong WenShuaishuai YuHuamin LiuXiaomin GaoLianguo ChenPublished in: Drug development and industrial pharmacy (2024)
according to these plants contain different mixtures of the four marker compounds.