Clinical and genetic factors associated with kidney tubular dysfunction in a real-life single centre cohort of HIV-positive patients.
S E SalvaggioA GiacomelliF S FalvellaM L OreniP MeravigliaC AtzoriE G I ClementiM GalliStefano RusconiPublished in: BMC infectious diseases (2017)
According to our results ABCC4 rs1751034 could be a genetic determinant of KTD; however validation studies are needed for therapy personalization. Noteworthy, a strong association between bone disease and KTD was also observed.
Keyphrases
- hiv positive
- end stage renal disease
- men who have sex with men
- antiretroviral therapy
- ejection fraction
- newly diagnosed
- chronic kidney disease
- south africa
- genome wide
- prognostic factors
- copy number
- stem cells
- patient reported outcomes
- bone mineral density
- bone marrow
- postmenopausal women
- hepatitis c virus
- body composition
- patient reported
- chemotherapy induced