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An Intervention Target for Myocardial Fibrosis: Autophagy.

Chunmiao LuYusong YangYaping ZhuShi-Chao LvJun-Ping Zhang
Published in: BioMed research international (2018)
Myocardial fibrosis (MF) is the result of metabolic imbalance of collagen synthesis and metabolism, which is widespread in various cardiovascular diseases. Autophagy is a lysosomal degradation pathway which is highly conserved. In recent years, research on autophagy has been increasing and the researchers have also become cumulatively aware of the specified association between autophagy and MF. This review highlights the role of autophagy in MF and the potential effects through the administration of medicine.
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