Quantitative proteomics analysis of lysine 2-hydroxyisobutyrylation in IgA nephropathy.

Shaoying HuangFengping ZhengHua LinXianqing ZhouHuixuan XuCantong ZhangWeier DaiBerthold HocherXinzhou ZhangDonge TangYong Dai

Published in: Clinical proteomics (2021)

Importantly, the abundance of lipocalin 2 was increased in the differentially expressed proteins, and a KEGG-based functional enrichment analysis showed that Khib proteins clustered in the IL-17 signaling pathway and phagosome category, which may have important associations with IgAN. Our data enlighten our understanding of Khib in IgAN and indicate that Khib may have important regulatory roles in IgAN.

Keyphrases

signaling pathway
pi k akt
electronic health record
high resolution
epithelial mesenchymal transition
machine learning
antibiotic resistance genes
data analysis
microbial community