Three-dimensional analysis of the characteristics of joint motion and gait pattern in a rodent model following spinal nerve ligation.
Takayuki SetoHidenori SuzukiTomoya OkazakiYasuaki ImajoNorihiro NishidaMasahiro FunabaTsukasa KanchikuToshihiko TaguchiTakashi SakaiPublished in: Biomedical engineering online (2021)
We revealed new quantitative parameters in an SNL rat model that are directly relevant to the neurological symptoms in patients with neuropathic pain, in whom the von Frey and thermal withdrawal tests are not used at all clinically. This new 3D analysis system can contribute to the analysis of pain intensity of SNL rats in detail similar to human patients' reactions following neuropathic pain.
Keyphrases
- neuropathic pain
- spinal cord
- spinal cord injury
- end stage renal disease
- endothelial cells
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- high resolution
- induced pluripotent stem cells
- chronic pain
- patient reported outcomes
- physical activity
- brain injury
- blood brain barrier
- patient reported